报告题目：BioElectronic Devices for POCTs
报告人：Prof. Chenzhong Li, Florida International University
Bioelectronics is the discipline resulting from the convergence of biology and electronics and it has the potential to significantly impact many areas especially in healthcare and medicine, food safety, homeland security, forensics, and protecting the environment. In addition to the well-known biological properties, various biomolecules also exhibits the unique electronics properties such as the cell membrane impedance, ion channel potentials, the redox properties of hemoproteins and the charge transfer properties of DNA. There is a great opportunity for dramatically increased synergy between electronics and biomolecules, fostered by-the march of electronics technologies to the nano/micro scale and by the discovery of novel electronic properties of biomolecules and various engineered nanomaterials.
Our research interest is to investigate the electronic properties of these nano-bio conjugations and further to integrate state-of-the-art MEMS/NEMS technology to develop miniaturized biomedical devices for both biomedical sensing diagnostics and environmental toxin monitoring.
Electronic biosensors are one of the most attractive approaches for rapid, accurate and sensitive diagnostics, especially for point of care testings (POCT). This lecture will outline our recent research activities for the fundamental study of electrical properties of biomolecules such as DNA and cells, as well as the development of a new generation of micro/nano electrical biosensors for bacterial whole cell analysis, chip based single cell trapping and high throughput assay and in-vitro mapping neuron activities.
Prof. Chenzhong Li earned his M.Sc in electrochemistry and PhD in bioengineering from Kumamoto University (Japan) in 2000. Before joining FIU in 2006, he held a position as a Research Officer at the Nanobiotechnology lab in the Canada National Research Council. Currently he is the director of the Nanobioengineering /Bioelectronics Lab and a professor in the Department of Biomedical Engineering at Florida International University. Dr Li’s research has focused primarily on the biomedical diagnostics, defense and environment related applications of bioelectronic sensing technology.
His research activities to date have resulted in 7 granted patents, more than 100 peer-reviewed journal papers with H-index 27 by 2015, 3 books and 7 book chapters, over 140 oral presentations including about 90 keynote/invited lectures and seminars worldwide. In addition to his publication activities, he is the guest editors of American Journal of Biomedical Science, and the Journal of Neuroscience and Neuroengineering. He is the associate editor of the journals of “Journal of Sensors”, “PLoS”, “Chemical Sensors”, “Science Bulletin” and “Applied Biochemistry and Biotechnology”. He also serves on several other journal editorial boards as well as being a reviewer and panelist for NIH, NSF, NSERC (Canada), NSFC (China), NES (UK) and Chinese 973 program. In recognition of his work, Dr. Li has received several awards and honors including the FIU faculty enhancement award (2008), 2011 the Kauffman Foundation Professor Award, 2014 FIU Outstanding Faculty Award in Research and 2014 Japanese JSPS visiting professor fellowship award.